GPAT Syllabus

According to Syllabus of GPAT2014

Total 50 (22 –Minor, 5-Mini Major, 2-Semi Major &  8 -Subject wise Major Test, 13 – Grand Major)Test will be conducted till GPAT-2014

SYLLABUS FOR MINOR TEST- 1

Pharmaceutics: Tablet & capsule

Pharmacology: General Pharmacology (Basics),

Medicinal Chemistry: Stereochemistry

Pharmaceutical Analysis: General Instrumental Analysis, U.V. Spectroscopy

Pharmacognosy: General Pharmacognosy (Quantitative microscopy including modern techniques used for evaluation)

SYLLABUS FOR MINOR TEST- 2

Pharmaceutics: Parenterals

Pharmacology & Medicinal Chemistry: Synthesis, SAR & Metabolism of drugs acting on ANS. Drugs acting on ANS (Adrenergic drugs, Anti-adrenergic, cholinergic & anti-cholinergic, drugs acting on autonomic Ganglion, skeletal muscle relaxants.)

Pharmaceutical Analysis: I R

Pharmacognosy: Glycosides & Biosynthetic pathways

Microbiology: Microbial Assay.

SYLLABUS FOR MINOR TEST- 3

Pharmaceutics: Drug Delivery Systems: NDDS (complete NDDS)

Pharmacology & Medicinal Chemistry of: Drugs Acting on Central Nervous System – Local & General anaesthetics, narcotic & non-narcotic analgesics

Pharmacognosy: Alkaloids

Microbiology: Application of microorganism in Bio-conversions & in pharmaceutical industry.

SYLLABUS FOR MINOR TEST- 4

Pharmaceutics: Aerosols & Pharmaceutical calculation

Pharmacology & Medicinal Chemistry of: Drugs Acting on Central Nervous – antiepilaptics, Sedatives & hypnotics, CNS Stimulents, antiparkinsonian & Psychopharmacological agents.

Pharmacognosy: Terpenoids, Volatile oils, & Tannins.

Pharmaceutical Analysis: NMR Spectroscopy

Biochemistry: Metabolism of Carbohydrates.

SYLLABUS FOR MINOR TEST -5

Pharmaceutics: Preformulation studies, Incompatibilities

Pharmacology & Medicinal Chemistry of: Autocoids (Histamine, Prostaglandins, leucotrienes, serotonin.), Anti Gout, Anti Arthritis

Pharmaceutical Analysis: Mass Spectroscopy, Thermal Techniques (DSC & DTA)

Microbiology: Serological & Diagnostic tests & Sterilization techniques.

Biochemistry: Metabolism of Lipids

SYLLABUS FOR MINOR TEST -6

Pharmaceutics: Pharmaceutical packaging (Containers & Closures, Pharmacopoeial (I.P.) test, standerds for Labeling)

Pharmacology & Medicinal Chemistry of: Drugs for Cardiovascular Disorders (Hypertension, Angina, MI, Congestive heart failure, antiarrhythmics,)

Pharmacognosy: Dietary antioxidants, Nutracuticals, Flavonoids

Biochemistry: Proteins, Nucleic Acids.

SYLLABUS FOR MINOR TEST- 7

Pharmaceutics: Liquid dosage forms (Emulsion & Suspension, Solution)

Pharmacology & Medicinal Chemistry of: Anti hyper lipidermic drugs, Diuretics, Anti diuretic, Hematinics, Anticoagulants, Vitamin K and hemostatic agents, Fibrinolytic and anti-platelet drugs, Blood and plasma volume expanders.

Pharmaceutical Analysis: Assay of different drugs, Fundamentals of volumetric analysis, Gravimetric, Titrametric analysis (Acid Base Titrations, Precipitation Titrations, Oxidation Reduction Titrations, Diazotization titrations, Kjeldahl method of nitrogen estimation, Karl-Fischer aquametry, Oxygen flask combustion method)

SYLLABUS FOR MINOR TEST- 8

Pharmaceutics: Pharmaceutical Excipients (vehicles, stabilizers, preservatives, suspending agents, emulsifying agents, solubilizers, colors, flavors and others).

Pharmacology & Medicinal Chemistry of: Drugs for Gastrointestinal & Respiratory system (Anti-asthmatic drugs including bronchodilators, Anti-tussives and expectorants, Respiratory stimulants, Antacids, Anti-secretory and Anti-ulcer drugs, Laxatives and anti-diarrhoeal drugs, Appetite Stimulants and Suppressants, Emetics and anti-emetics, Miscellaneous: Carminatives, demulcents, protectives, adsorbents, astringents, digestants, enzymes and mucolytics )

Pharmaceutical Analysis: Gasometry; Extraction procedures including separation of drugs from excipients.

SYLLABUS FOR MINOR TEST- 9

Pharmaceutical Engineering: Importance of unit operations in manufacturing; Stoichiometry, Fluid Flow, Heat transfer, Evaporation, Distillation, Drying, Size Reduction.

Pharmacology & Medicinal Chemistry of: Drugs acting on uterus, Diabetes, thyroid, Bioassays

Pharmaceutical Analysis: Chromatographic Techniques.

SYLLABUS FOR MINOR TEST -10

Pharmaceutics: Mixing,Filtration, Centrifugation & Rehology, Crystallization ,Dehumidification and Humidity Control, Refrigeration and Air Conditioning

Pharmacology & Medicinal Chemistry of: Steroidal Drugs, Antifertility drugs

Clinical Pharmacy: Therapeutic Drug Monitoring, Clinical Pharmacokinetics and individualization of Drug therapy, Drug delivery systems and their Biopharmaceutic & Therapeutic considerations, Drugs used during infancy and in the elderly persons (Pediatrics & Geriatrics), Drugs used during pregnancy, Drug induced diseases, The basics of drug interactions, General principles of clinical toxicology

SYLLABUS FOR MINOR TEST -11

Cosmeticology and Cosmetic Preparations: Fundamentals of cosmetic science, structure and functions of skin and hair. Formulation, preparation and packaging of cosmetics for skin, hair, dentifrice and manicure preparations like nail polish, nail polish remover, Lipsticks, eye lashes, baby care products etc.

Pharmacology & Medicinal Chemistry of: Sulfonamides, All Antibiotics-Penicilline, cephelosoprin, tetracycline, chloramphenicol,  Aminogylcoside, Macrolide, Lincosamide, other Antibiotics-  Anti tubercular drugs, Anti leprotic drugs

Pharmaceutical Analysis: Polarimetry & Coulometry

Pharmacognosy:Role of plant-based drugs on National economy (Full detail of this topic check GPAT-13 syllabus)

SYLLABUS FOR MINOR TEST- 12

Pharmacology & Medicinal Chemistry of: Anti viral, Anti fungal Anti malarial, Anti cancer, Anti protozoal, Immunosuppressives and immunostimulants, Vitamins, Diagnostic agents

Pharmaceutical Analysis: Flame photometry, Potentiometry  Conductometry,  Fluorimetry

Biochemistry: Biochemical role of hormones, Vitamins, Enzymes, Enzyme immobilization, Bioenergetics.

SYLLABUS FOR MINOR TEST -13

Quality assurance:- GLP, ISO 9000, TQM, Quality Review and Quality documentation, Regulatory control, regulatory drug analysis, interpretation of analytical data, Validation, quality audit: quality of equipment, validation of equipment, validation of analytical procedures.

Pharmaceutical Chemistry: Importance of inorganic compounds in pharmacy and medicine -(Full detail of this topic check GPAT-13 syllabus)

Pharmacognosy: FIBERS:- Study of fibers – cotton, silk, wool, nylon, glass-wool, polyester and asbestos. Marine pharmacognosy: Novel medicinal agents from marine sources. Natural llergens and photosensitizing agents and fungal toxins.

SYLLABUS FOR MINOR TEST -14

Pharmaceutics: Material of Construction, Material Handling Systems, Corrosion

Pharmaceutical Chemistry: Behaviour of Gases, Liquid State, Solutions, Photochemistry, Thermodynamics, Chemical Kinetics, Quantum Mechanics

Pharmacology:Pathophysiology of common diseases; Basic Principles of Cell Injury and Adaptations (Full detail of this topic check GPAT-13 syllabus)

SYLLABUS FOR MINOR TEST -15

Pharmaceutics: Plant location, Industrial Hazards and Safety Precautions, Automated Process Control Systems

Pharmaceutical Chemistry: Atomic Structure, Chemical Bonding,Acids and bases, Alkanes, Alkenes, Alkynes, Reactive intermediates- carbocations, carbanions, carbenes and nitrenes

Pharmacology: Principles of Toxicology:- Definition of poison, general principles of treatment of poisoning with particular reference to barbiturates, opioids, organophosphorous and atropine poisoning, Heavy metals and heavy metal antagonists.

Pharmacognosy: Classification of Drugs:- Morphological, taxonomical, chemical and pharmacological classification of drugs; Study of medicinally important plants belonging to the families with special reference to: Apocynacae, Solanaceae, Rutacease, Umbelliferae, Leguminosae, Rubiaceae, Liliaceae, Graminae, Labiatae, Cruciferae, Papaveraceae;

SYLLABUS FOR MINOR TEST- 16

Pharmaceutics: Community Pharmacy,Organization and Structure of hospital pharmacy, Hospital Formulary

Pharmacology: Common clinical laboratory tests and their interpretation; Important Disorders of Organs, Systems and their Management (Full detail of this topic check GPAT-13 syllabus)

Pharmaceutical Chemistry: Cyclic analogs, Dienes, Benzene, Polynuclear aromatic compounds, Arenes, Alkyl halides, Alcohols, Ethers, Epoxides, Amines, Phenols, Aldehydes and ketones, Carboxylic acids, Functional derivatives of’ carboxylic acids, a,ß-Unsaturated carbonyl compounds, Electrophilic and Nucleophilic Addition Reactions; Rearrangements.

SYLLABUS FOR MINOR TEST- 17

Pharmaceutics: Drug Store Management and Inventory Control, Drug distribution Systems in Hospitals, Central Sterile Supply Unit and their Management, Manufacture of Sterile and Non-sterile Products, Drug Information Services, Records and Reports, Nuclear Pharmacy

Pharmaceutical Chemistry: Conservation of Orbital Symmetry and Rules: Electrocyclic, Cycloaddition and Sigmatropic reactions; Neighboring group effects; Catalysis by transition metal complexes; Heterocyclic Compounds: Nomenclature, preparation, properties and reactions of 3, 4, 5, 6 & 7-membered heterocycles with one or two heteroatoms like 0, N, S. Chemistry of lipids, Carbohydrates and Proteins.

Pharmacognosy: Herbs as health foods. Herbal cosmetics. Standardization and quality control of herbal drugs, WHO guidelines for the standardization of herbal drugs

Pharmaceutical Jurisprudence: D & C Act (Forms, Schedules, Specific area, administration to the act & Different Indian laboratories)

SYLLABUS FOR MINOR TEST -18

Pharmaceutics:Biopharmaceutical Classification System (BCS) of drugs, Semisolid Dosage Forms, Ophthalmic Preparations

Pharmacognosy: Quality Control of Crude Drugs: Adulteration of crude drugs and their detection by organoleptic, microscopic, physical, chemical and biological methods and properties. Introduction to Active Constituents of Drugs: Their isolation, classification and properties.

Jurisprudence: Medicinal & Toilet Preparations (Excise Duties) Act 1955; Narcotic Drugs & Psychotropic Substances Act 1985 & Rules; Drugs Price Control Order; Poisons Act 1919; Drugs and Magic Remedies (Objectionable Advertisements) Act 1954

Microbiology: Actinomycetes, bacteria, rickettsiae, spirochetes and viruses, Identification of Microbes, Control of microbes by physical and chemical methods:

SYLLABUS FOR MINOR TEST- 19

Pharmaceutics: Principle involved and procedures adopted in dispensing of :

Typical prescriptions like mixtures, solutions, emulsions, creams, ointments, powders, capsules, pastes, jellies, suppositories, ophthalmic, pastilles, lozenges, pills, lotions, liniments, inhalations, paints sprays tablet triturates, etc

Immunology: Immunology and Immunological Preparations, Genetic Recombination, Antibiotics:

Performance evaluation methods: In-vitro dissolution studies for solid dosage forms methods, interpretation of dissolution data. Bioavailability studies and bioavailability testing protocol and procedures. In vivo methods of evaluation and statistical treatment. GMP and quality assurance, Quality audit. Design, development, production and evaluation of controlled/sustained/extended release formulations.

SYLLABUS FOR MINOR TEST -20

Biopharmaceutics- Compartment model- ,Clinical Pharmacokinetics: (Full detail of this topic check GPAT-13 syllabus)

Pharmacognosy: Cultivation, Collection, Processing and Storage of Crude Drugs: Factors influencing cultivation of medicinal plants, Types of soils and fertilizers of common use. Pest management and natural pest control agents, Plant hormones and their applications, Polyploidy, mutation and hybridization with reference to medicinal plants.

Pharmaceutical Chemistry: Principles of Drug Design (Theoretical Aspects): Traditional analog and mechanism based approaches, QSAR approaches, Applications of quantum mechanics, Computer Aided Drug Designing (CADD) and molecular modeling;

SYLLABUS FOR MINOR TEST -21

Pharmaceutics: Introduction to Physical pharmacy; Matter, Properties of Matter,

Surface and Interfacial Phenomenon,Viscosity and Rheology,Dispersion Systems,

Complexation, Kinetics and Drug Stability, Micromeretics and Powder Rheology

Pharmacology:Adverse drug reaction & Drug interaction, Plant Hormones,

Pharmaceutical Analysis: ESR, XRD,

Pharmacognosy: Biosynthetic pathways, Isolation & Characterization of different secondary metabolites, Saponins, Steroids, Immunomodulaters.

SYLLABUS FOR MINOR TEST -22

Jurisprudence: Medical Termination of Pregnancy Act 1970 & Rules 1975; Prevention of Cruelty to Animals Act 1960; States Shops & Establishments Act & Rules; Insecticides Act 1968; AICTE Act 1987; Factories Act 1948; Minimum Wages Act 1948; Patents Act 1970. A brief study of the various Prescription/Non-prescription Products. Medical/Surgical accessories, diagnostic aids, appliances available in the market.

Pharmacognosy: Studies of Traditional Drugs (Full detail of this topic check GPAT-13 syllabus)

Pharmaceutics: ICH Guidelines for stability testing of formulations.

Biotechnology: Plant Tissue culture

Pharmacology: Concept of Essential Drugs and Rational Drug use